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Patients on other dual therapy were switched to metformin HCl 1500 mg/day and rosiglitazone 4 mg/day in a dose titration/stabilization run-in period of up to 20 weeks in duration
Animal studies showed accelerated dermal healing in normal rats, steroid-treated rats, diabetic mice, and aged mice, all populations with compromised healing capacity similar to chronic eczema patients
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It is a narrative rather than a systematic review
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