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The effect is dose-dependent: concentrations of 5 to 10% show the best results, while concentrations below 2% produce modest effects
In support, increased BDNF levels in the hippocampus have been found in post-mortem brains from individuals treated with antidepressant medications 10
This process is marked by chronic low-grade inflammation (inflammaging), diminished adaptive immunity, and a skewed CD4+/CD8+ T cell ratio, leaving older adults more vulnerable to infection, cancer, and poor vaccine responses [47]
Individuals who are pregnant, breastfeeding, taking medications, or with medical conditions should consult a healthcare professional before use
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