In fact, ROS-modulating therapies share certain similarities with existing treatments such as chemotherapy and immunotherapy, that is, pro-oxidative stress strategies to further kill tumor cells and other cells, which has been recognized as a promising approach to improve treatment outcomes for decades [564, 565]
PLoS One 7:e31286 Liu GL, Han NZ, Liu SS (2018) Caffeic acid phenethyl ester inhibits the progression of ovarian cancer by regulating NF-B signaling
Higher Circulating Trimethylamine N-oxide Sensitizes Sevoflurane-Induced Cognitive Dysfunction in Aged Rats Probably by Downregulating Hippocampal Methionine Sulfoxide Reductase A
Currently, conventional probiotic formulations are already employed in clinical settings as adjunctive therapy for colorectal cancer, largely to minimize surgical complications and alleviate chemotherapy-induced toxicity (304)
The dosage is increased gradually to either 5 mg , 10 mg , or 15 mg once weekly to improve tolerance
Pincemail J, Cavalier E, Charlier C, CheramyBien J-P, Brevers E, Courtois A, et al