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At 3 weeks follow-up, HR with liraglutide was significantly elevated compared with placebo (n = 17) for the whole 24-h period, day- and nighttime (least squares mean differences were 5.2, 4.6, and 7.3 bpm, respectively) [26]

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Mice injected with amine-modified PS-NPs (80 nm) and carboxylated PS-NPs at 5 mg/kg showed a significant reduction in body weight, suggesting a negative NP impact on mices health [46]

In many fibroblast driven diseases, an inflammatory response often precedes the activation of myofibroblasts