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Consequently, increasing the activity of phase II enzymes, such as glutathione S-transferases (GSTs) and NQO-1, may help prevent cancer by enhancing the elimination of potential carcinogens (see the Nrf2-dependent antioxidant pathway) (63)
The micronuclei are sensed by cGAS and lead to the activation of STING, which further induces type I IFN production (37)
For example, in the study by Novinscak et al
Journal of Pharmacology and Experimental Therapeutics, 377(3), 417-440
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(PubMed) Bressa GM
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