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Nor does it explain another surprising finding from the study: men taking these weight-loss treatments appeared to face three times the risk of vision loss compared to women

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Although PF-05231023 demonstrated pharmacodynamic effects when dosed weekly or twice-weekly in humans, the unmodified N- and C-termini of the FGF21 moities resulted in a short (approximately 8 h) half-life for the intact C-terminal domain of FGF21 (183)

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