It is especially interesting as a treatment for osteoarthritis, as it has shown better results than cortisone and hyaluronic acid injections for early-to-moderate osteoarthritis symptoms
It works by mimicking the GLP-1 hormone to reduce hunger and control blood sugar levels
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Slowing the ramp to the label cadence (2.5 mg start, 2.5 mg steps, four-week holds) dropped that to mid-single digits at every maintenance dose, at no cost to the 12-week result, and the dedicated slow-titration trial reached placebo range. Reaching 15 mg is not the problem
The therapeutic window appears quite wide, with most users experiencing benefits without significant side effects across a range of doses
