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These agents effectively improved glucose and lipid metabolism in clinical trials 12,13

doi:10.1530/eje.0.1510483

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Oral semaglutide (Rybelsus) should not be used after a confirmed semaglutide allergy

Additionally, a prespecified exploratory analysis showed 60% of participants on the highest, 15-mg dose of tirzepatide (Eli Lilly) achieved a composite endpoint of an HbA1c of 6.5% or lower and weight loss of 10% or greater with no reports of severe hypoglycemia, compared with 22% of participants assigned 1 mg semaglutide (Ozempic, Novo Nordisk)