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Mercer, 2024
Tier 3: avoid or use with extreme caution Mineral oil
Melanotan I is a synthetic linear tridecapeptide analogue of alpha-melanocyte-stimulating hormone, sequence Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH (CHNO, 1646.9 g/mol, CAS 75921-69-6), catalogued in the literature as afamelanotide, as NDP-alpha-MSH, and in analogue notation as [Nle, D-Phe]-alpha-MSH
LiuYYiehLYangTDrinkenburgWPeetersPStecklerTet alMetabolomic biosignature differentiates melancholic depressive patients from healthy controls
Some animal studies suggested a regulatory role of dopaminergic neurons in Gln synthesis 28,50,51
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