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GHKs histidine residue provides nitrogen coordination sites that stabilize Cu in a square planar geometry, creating a complex with a dissociation constant (Kd) around 10 Mamong the highest copper-binding affinities of any naturally occurring peptide

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Suggested Dosing Chemotherapy Adjunct 600 mg/day IM days 2-5 of chemotherapy 1.5 g/m IV before chemotherapy Male Infertility 600 mg IM qOD x 2 months Oral 250 mg PO qDay Dose range: 50-600 mg/day Inhaled 600 mg NEB BID Inborn Errors of Metabolism of Glutathione (Orphan) Liposomal glutathione: Support of glutathione deficiency in individuals with inborn errors of metabolism of glutathione (IEMG) Orphan indication sponsor Your Energy Systems, LLC

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