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Participants who started anti-nausea medication in week 1, before symptoms became severe, reported 40% less intense nausea during peak weeks 6-8 compared to those who waited until symptoms were already unbearable

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Cagrilintide was specifically engineered with molecular modifications to resist rapid breakdown in the body and bind effectively to amylin 1 and 3 (AMY1R, AMY3R) receptors in the brain, allowing for a more stable, once-weekly dosing regimen compared to the multiple daily injections required for older amylin analogues like pramlintide

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