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Time of day Twice-daily dosing (most common): Morning: 30-60 minutes before breakfast Evening: 30-60 minutes before dinner OR before bed Consistent timing each day helps Once-daily dosing: Morning preferred (on empty stomach) Or before bed for healing during sleep Choose what fits your schedule Does timing matter much

Additionally, individuals taking medications that may interact with B12, including metformin or proton pump inhibitors, should consult a healthcare provider before starting supplementation

Liver If you have liver health concerns, it is important to discuss them with your doctor before starting treatment with Full-B12 Injection

However, years later talking with a friend and Dr about some issues I was having potentially related to my low iron and my low platelet count, which no one seems able to pin point a cause for he recommended B12 shots

References Dimet-Wiley, A., Wu, Q., Wiley, J., Eswar, A., Neelakantan, H., Savidge, T., & Watowich, S

Some people notice improvements in energy and mood within a few days to a couple of weeks