Platinum drugs are metabolised by glutathione S -transferase P1 ( GSTP1) , which is abundantly, but variably expressed in ovarian tumours
However, their high metabolic risks, including weight gain, diabetes, and lipid abnormalities, 1 deter treatment adherence 2 and increase cardiovascular disease risk and related mortality, 3,4 making it challenging for clinicians to balance psychiatric and physical health
Beaulieu, J.-M., Gainetdinov, R
For patients where homocysteine was measured and found to be high, I want it down below 15 mol/L on recheck before proceeding
GLP-1s and other FDA-approved drugs have objective markers to establish whether they actually work, such as HbA1c levels for blood sugar and measurable weight loss
Cells 8(4):323 Tanaka T, Matsushita T, Nishida K, Takayama K, Nagai K, Araki D, Matsumoto T, Tabata Y, Kuroda R (2019) Attenuation of osteoarthritis progression in mice following intra-articular administration of simvastatin-conjugated gelatin hydrogel