(Source) Intestinal obstructions: One study found that participants who took an incretin-based drug (e.g, a GLP-1 like Ozempic) were over 4.5 times more likely to report having an intestinal obstruction than those taking other diabetes medications
When this pathway is activated, the body suppresses inflammation, activates detoxification, and promotes antioxidants to exert their effects
That was true for fewer than 7% of semaglutide users who lost the same percentage of body weight
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GLP-1 medications counteract some of these hormonal effects, so you still lose unwanted weight
Challenge 2: nausea around meals Nausea peaks in the 24-48 hours after injection and during dose escalations