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The carboxy-terminal MRR of MARCHF6 binds directly to the amino terminus of NADPH and E3 ligase, and NADPH is related to the REDOX state of the cell

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Bullon, N., Seyfoddin, A., Dezfooli, S

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3 The ubiquitin-proteasome system (UPS) pathway Eukaryotic cells rely heavily on the UPS to regulate various cellular processes, including protein homeostasis, cell cycle progression, and response to stress, signal transmission, and transcriptional activation (Myung et al., 2001