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The study confirmed that FOXO4-DRI binds directly to the disordered p53 TAD2 domain and forms a transiently folded complex a disordered-to-ordered transition involving both the FOXO4-derived region of the DRI peptide and its cationic cell permeability element
Stewart, A., Thomas, B
Walle T, Hsieh F, DeLegge MH, Oatis JE Jr., Walle UK
The publication is indexed in the National Library of Medicine: Effect of Peptide Preparation Epithalamin on Circadian Rhythm of Epiphyseal Melatonin-Producing Function in Elderly People (Bull Exp Biol Med 2004)
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[2] It is one of the few peptides that has crossed the boundary from laboratory research into widespread commercial skincare products, appearing in serums, creams, and post-procedure treatments marketed for anti-aging effects
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