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The upper left quadrant refers to the cholestasis range

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Patients experiencing shortness of breath while taking tirzepatide should seek immediate medical attention if they develop any of the following warning signs: Seek emergency care immediately (call 911) for: Sudden onset of severe shortness of breath or difficulty breathing Chest pain, pressure, or tightness accompanying breathing difficulties Rapid heart rate, palpitations, or irregular heartbeat Swelling of the face, lips, tongue, or throat (suggesting anaphylaxis) Wheezing, stridor, or audible breathing difficulty Confusion, lightheadedness, or loss of consciousness Blue discoloration of lips or fingertips (cyanosis) These symptoms may indicate serious conditions requiring urgent evaluation, including acute coronary syndrome, pulmonary embolism, severe allergic reaction, or acute heart failure

Yamamoto K, Rakugi H