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In contrast, in the unilateral ureteral obstruction (UUO) animal model and clinical samples, the expression of the E3 ligase HUWEI was decreased and that of EGFR was increased

Laboratory research expanded into studies exploring its signaling behavior and interaction with cellular regulatory systems

It modulates cardiac protection via regulation of EphA2 tyrosine phosphorylation

Potential areas of scientific interest include: Interaction with signaling pathways involved in tissue physiology Influence on vascular-related biological mechanisms Engagement with molecular processes associated with cellular response Individual responses may vary, and outcomes are not guaranteed

2014 Nov 19;19(11):19066-77