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Ishihara, Y., Nishiguchi, S., Branch, J

Heat relaxes tense muscles, while cold reduces inflammation and numbs sharp pain

Based on studies suggesting people taking a glucagon-like peptide-1 (GLP-1) could be less likely to develop Alzheimers, Novo Nordisk set up two large trials of its drug, semaglutide sold as the popular diabetes and obesity drugs Ozempic and Wegovy

Symptoms are more likely to appear or temporarily worsen when the dose is increased , which is expected and reflects how the body adjusts to higher levels of the medication rather than a sign that treatment is unsafe

doi:10.1056/NEJMoa1607141 Gerstein HC, Colhoun HM, Dagenais GR, et al

All of these medications have different dosing schedules and frequencies