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While systemic injection also delivers peptides to the brain via blood circulation, nasal delivery may provide more direct CNS access for some portion of the dose

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[1] Without intrinsic factor, dietary B12 cannot be absorbed effectively, leading to deficiency regardless of dietary intake

The benzyl alcohol preservative helps maintain sterility of the line between uses

Benzyl alcohol, the preservative in bacteriostatic water, is contraindicated in neonates and premature infants due to the risk of gasping syndrome, as noted in BNF and MHRA guidance

CDC (2023) General Best Practice Guidelines for Immunization: Vaccine Administration Related research, protocols, and guides Explore the available research context, protocol variants or comparisons, and practical guides