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Zhang et al., 2025)

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This suggests that hsa_circ_0004870 through RBM39, may play a critical role in the development of enzalutamide resistance [137]

Rarely, some have reported cramping or abdominal discomfort.These tend to be transient

She emphasizes the importance of drinking plenty of fluids to stay well hydrated

In carefully selected, well-tolerant patients, some clinicians may consider starting at 5 mg with close follow-up, but the labeled 2.5-mg on-ramp remains the safest default