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Nature medicine 19, 576585 (2013)
Most available studies are exploratory, and large, wellcontrolled randomized trials are lacking
Calculation of IC 025 for these drugs is consistent with the procedure described in section 2.5
Additionally, lipoic acid lowered serum markers associated with heart damage and inflammation, including brain natriuretic peptide, TNF-alpha, malondialdehyde, and neurotensin levels, but it did not significantly affect heart ejection fraction (Werida 2022)
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