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Journal of Pain and Symptom Management, 32(6), 551-559

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(5) Notably, this stimulation seems selective for collagen, as non-collagen protein synthesis apparently remained unaltered, suggesting the action may not have been a general support for protein production

Beyond mtROS, other danger signals including ATP, crystalline substances, and membrane damage also contribute to NLRP3 activation in the hyperglycemic, AGE-rich, and oxidative DW microenvironment (Wang et al., 2025a)

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