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The peptide samples were loaded on a nanoscale capillary reverse-phase C18 column using a high-performance LC (HPLC) system (Thermo Fisher Scientific UltiMate3000) and eluted by a gradient

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OSAS/hypoxia acts as a trigger for localized hepatic oxidative stress and inflammation that promotes the progression of NASH and hepatic fibrosis [109, 110]

Esto ayuda a generar sensacin de saciedad y, dentro de una dieta equilibrada, favorece la prdida de peso.* Adems, el glucomanano ayuda a mantener los niveles normales de colesterol sanguneo, siempre que se consuma en las cantidades recomendadas y como parte de un estilo de vida saludable.* *El efecto beneficioso sobre la prdida de peso se obtiene con una ingesta diaria de 3 g de glucomanano, repartidos en tres dosis de 1 g cada una, junto con 1-2 vasos de agua antes de las comidas y en el marco de una dieta equilibrada

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