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When you eat, GLP-1 is released into your bloodstream, stimulating insulin secretion from the pancreasbut only when your blood sugar levels rise, such as after a meal

Importantly, when GLP-1 medications are added to insulin or sulfonylureas, doses of these medications may need reduction to prevent hypoglycaemia

Those who could become pregnant should talk with their clinician about pregnancy testing, contraception, and the timing around stopping a GLP-1 medication before trying to conceive, since these drugs are not approved for use during pregnancy, Holt says

doi: 10.1172/JCI36843 98 KennedyKMScarbroughPMRibeiroARichardsonRYuanHSonveauxPet al

Abdollahi et al

These findings may indicate an infection or other complication requiring medical evaluation