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Reactive management at this tier is consistently slower than prophylaxis

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Clinical review is recommended when symptoms persist beyond four to six weeks, there is a significant impact on nutrition or hydration, or side effects are severe or worsening

In clinical trials, people on Tirzepatide experienced an average weight loss of 15.3% after a year, compared to 8.3% for those on Semaglutide

These findings provide a mechanistic basis for the hypothesis that GLP-1 agonists could help curb addictive behaviors in humans

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