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Authors Author Contributions SK, BRP, SKP and DKS: In silico study, validation, visualization

1 Improved Blood Glucose Control: GLP-1 agonists can reduce HbA1c (a marker of average blood glucose levels over 3 months) by around 1% to 2%, which is comparable to or even exceeds other diabetes treatments

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How GLP-1 Medications Work With these particular weight loss/T2D medications, active ingredients Semaglutide and tirzepatide mimic GLP-1 (Glucagon-like peptide-1), the naturally occurring hormone produced in the GI tract

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Drug Discov Today 21(5):802818 Hamilton A, Hlscher C (2009) Receptors for the incretin glucagon-like peptide-1 are expressed on neurons in the central nervous system