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These larger molecules show reduced renal clearance as well as being DPP-4 resistant

Genazzani AD, Lanzoni C, Ricchieri F, Santagni S, Rattighieri E, Chierchia E, et al

In animal models, where depression was induced by lipopolysaccharide, which is an inflammatory compound, BSO reduces that lipopolysaccharide-induced inflammation and alleviates depressive behaviors

Taking self-treatment may increase the risk of its side effects

For Novo Nordisk, the launch strengthens its foothold in the fast-growing diabetes and obesity market, while for India, it could mark the start of a new chapter in chronic disease management.

Clinicians should document pregnancy intentions, review contraceptive options, and outline a clear discontinuation plan if conception is desired