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Such smart nanoplatforms increase drug accumulation at tumor sites while minimizing toxicity to normal tissues
The receptor population recovers within 710 days of peptide cessation, which is why cycling protocols (5 days on, 2 days off, or 3 weeks on, 1 week off) prevent tolerance buildup
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The substrates for peroxidation reactions during ferroptosis are phospholipids with polyunsaturated fatty acid tails (PL-PUFAs), as they inherently possess intrinsic susceptibility to peroxidation reactions
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