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on 24 patients with generalized vitiligo and 20 healthy controls found statistically significant higher levels of superoxide dismutase activity in erythrocytes, serum MDA, and nitric oxide (NO) and statistically significant lower levels of glutathione and glutathione peroxidase in the patients of vitiligo compared to the controls.[] Secondary to the oxidative stress, the polyunsaturated fatty acids undergo peroxidation resulting in formation of free radicals

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Primers (Integrated DNA technologies, Singapore) used for PCR reactions were listed in Table 1

Following exposure to ATZ, the Nrf/HO-1 pathway was increased at the mRNA level in the testis tissue, suggesting that ATZ has harmed rats reproductive systems through oxidative stress 73

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Why Glutathione Is Called the Master Antioxidant