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Obesity: Global epidemiology and pathogenesis (in Eng)

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An imbalance between the two can create oxidative stress that opens the gateway for aging as well as diseases such as high blood pressure, various cancers, and Alzheimers disease, and alcoholic liver disease

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[11] Long-term metformin therapy reduces calcium-dependent intrinsic-factor binding, lowering B12 absorption and potentially necessitating higher or more frequent parenteral doses