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Baer, S
Ultra-thin sections were counterstained on a drop of UranyLess solution (Electron Microscopy Sciences, Hatfield, PA, USA) and 0.2% lead citrate
109 Additionally, metabolites such as 2-hydroxyglutarate, succinate, and fumarate derived from mutations in IDH1/2, FH, and SDH inhibit DNA repair pathways by repressing lysine demethylase KDM4B, resulting in abnormal excessive H3K9 methylation at DNA break sites, impairing recruitment of TIP60 and ATM, reducing end resection, and decreasing recruitment of downstream repair factors
Glutathione levels tend to decline with age, and research has suggested a potential link between low glutathione levels and age-related diseases, such as cardiovascular disease, neurodegenerative disorders, and cancer
doi: 10.1016/j.ijbiomac.2017.06.055 161
La evaluacin de la lipoperoxidacin refleja el dao sufrido por reacciones peroxidativas de los cidos grasos poliinsaturados (PUFA) en la membrana, esta determinacin de MDA se considera un marcador de estrs oxidativo
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