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IGF-1 LR3 Research Guide: Mechanism, Pharmacology, Laboratory Use IGF-1 LR3 is a long-acting analogue of insulin-like growth factor 1 with an Arg substitution at position 3 and a 13-amino-acid N-terminal extension

You can find more technical data on Nature.com regarding peptide signaling

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The term metabolite is usually used to describe small molecules, while broader application is often practiced

Macrophages secrete cytokines, including interleukin-1 (IL-1), interleukin-6 (IL-6), fibroblast growth factor (FGF), PDGF, EGF, tumor necrosis factor (TNF), and TGF, which coordinate the migration of keratinocytes and fibroblasts to the wound (Sindrilaru and Scharffetter-Kochanek, 2013)

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