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This 'no pain, no gain' way of thinking can make people ignore early warnings of bigger problems

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Gll N, Kobelt D, Brim H, Rahman S, Timm L, Smith J, Soleimani A, Di Marco S, Bisti S, Ashktorab H, Stein U (2020) Saffron crudes and compounds restrict MACC1-dependent cell proliferation and migration of colorectal cancer cells

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The impact that GLP-1s can have on weight loss has also caught the attention of the wider public and the result has been skyrocketing market values for companies like Eli Lilly and Novo Nordisk

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ApoE 4 has been demonstrated to impair cerebral insulin signaling by binding to the insulin receptor and preventing insulin receptor trafficking [151]

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Currently, a major gap in the field that applies here relates to the need for a diagnostic biomarker in humans that correlates with pre-neoplastic disease progression (e.g., indicating a high grade PanIN)

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