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Springer International Publishing, pp 297319

doi: 10.1001/jama.2017.14752 39 WilliamsDMRuslanAMKhanRVijayasingamDIqbalFShaikhAet al

7 As the first approved dual agonist targeting both GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) receptors, tirzepatide demonstrated weight loss exceeding 20% in its pivotal trials, establishing a new therapeutic ceiling

It works best as a supportive metabolic tool, not a standalone solution

United State Food and Drug Administration, center for drug evaluation and research

coli UTIs include those with urinary catheters, anyone with a history of recurrent UTIs, and people who recently had a course of antibiotics