Once in the brain it acts as a neuroprotective and antioxidant agent and supports energy metabolism
G protein-coupled receptor (GPCR) is a 7-transmembrane protein receptor containing a G protein-binding region in the cytoplasm and a ligand-binding region outside the cell
Stub your toe, and pain receptors send a clear message to your brain
The pharmaceutical industry is developing newer and potentially cheaper or more effective molecules that target GLP-1 and associated pathways (for example, the so-called dual- and triple-agonists tirzepatide, retatutride and orfoglipon) 257,258

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