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Before & After: Setting Realistic Tirzepatide Expectations The ideal candidate for tirzepatide therapy is typically someone with a BMI of 30 or higher, or a BMI of 27 or higher accompanied by weight-related comorbidities such as hypertension, high cholesterol, insulin resistance, or type 2 diabetes
The SURMOUNT-1 Phase 3 trial published in the New England Journal of Medicine demonstrated 20.9% mean body weight reduction at 72 weeks on tirzepatide 15mg weekly versus 3.1% with placebo
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