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Near-infrared resonant nanoshells for combined optical imaging and photothermal cancer therapy

So this is called uncoupling it

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This research was funded by the NIH National Center for Research Resources, the National Center for Advancing Translational Sciences (UL1TR001449), and the UNM Department of Pathology

Taken together, these in vivo data from multiple CRC models support our conclusion that inhibition of mitochondrial metabolism by metformin treatment can enhance the response of 5FU treatment by increasing tumour cell death and impeding tumour growth