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Itching and Dryness Some users report itching or dryness around the cold sore area after using Abreva

[11] [12] Vitamin B12 (cobalamin) is essential for maintaining the myelin sheath that protects nerve fibers, and deficiency can cause or worsen peripheral neuropathy, presenting with symptoms similar to diabetic neuropathy

These combined effects reduce tissue swelling, oxidative damage, and cell apoptosis, supporting models of inflammation recovery, joint repair, and chronic pain modulation

The concerns about long-term safety are real and, so far, unresolved

Patients who feel dramatically better and return to full training too soon before the tissue has actually repaired structurally are at elevated risk of re-injury

Electrolyte Balance: In cases of electrolyte imbalance (such as from vomiting or diarrhea), IV infusion helps replenish important salts like sodium and potassium, which are crucial for heart, muscle, and nerve function