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Diarrhoea is a common gastrointestinal side effect experienced by many people taking weight management injections such as semaglutide (Wegovy) and tirzepatide (Mounjaro)

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it also activates the GIP (glucose-dependent insulinotropic polypeptide) receptor

Moreover, downregulation of IGF-1R, obtained by antisense strategies, has been reported to elicit a host response leading to eradication of surviving malignant cells in vivo (Resnicoff et al, 1996)

Originally developed to treat type 2 diabetes, the drug also provides weight loss benefits, and more Americans than ever are using it for just that

[2] Examples beta blockers are atenolol, metoprolol, nadolol, pindolol, propranolol, and timolol