The role of GLP-1R in type 2 diabetes mellitus (T2DM) is highlighted, emphasizing its pivotal contribution to glucose homeostasis, promoting -cell proliferation, and facilitating insulin release
This metabolic profile is identical to that observed in isolated sulfite oxidase deficiency (ISOD), an inherited condition caused by mutations in the SUOX gene that codes for sulfite oxidase (29)
The hair growth cycle's natural timeline explains this delay: follicles that enter telogen phase require several months before the hair shaft is released and shedding becomes noticeable
Cardio: Aerobic exercise, such as brisk walking, jogging, or cycling, has been shown to increase GLP-1 levels and improve blood sugar regulation
It is not recommended due to the risk of euglycemic diabetic ketoacidosis
It has proven CV safety with tolerable GI AE at par with other GLP-1RAs