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In some cancer contexts, lowering oxidative stress may be beneficial
Future Perspectives The scientific studies on seleno-GPxs have so far led to the understanding that the physiological role of seleno-GPxs is not only limited to detoxification of peroxides, but also involves regulating signaling pathways (such as chromatin remodulating, NF-B activation, insulin signaling, mitochondrial integrity, and ferroptosis, among others) [1, 8,9,10]
Five children with neither supplementation nor a known chronic illness were later diagnosed with a malignancy, including chronic myeloid leukemia
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doi: 10.17925/EE.2025.21.2.5, 49
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