However, adjustments may be considered if: Glycaemic targets are not achieved : Your doctor may increase to the next available dose strength Intolerable side effects persist : A temporary dose reduction or slower titration may be appropriate Weight loss plateaus (for weight management indications): Dose optimisation may be discussed Renal function changes : Monitoring may be increased, though most GLP-1s don't require dose adjustment Other medications are added or removed : Particularly other glucose-lowering agents Important considerations during dose changes: Never skip doses or double up if you miss an injectionfollow the specific guidance in your patient information leaflet For missed doses, each product has different instructions: Semaglutide (Ozempic/Wegovy): If within 5 days, take as soon as possible
Pharmacists: Are you seeing a trend toward shorter "pulse" therapies rather than lifelong PPI use in your practice
Individuals with a BMI of 27 kg/m or greater (classified as overweight) who also have at least one weight-related comorbidity, such as high blood pressure, type 2 diabetes, or high cholesterol
Mary Claire Haver, who is on the kind of zero bullshit policy with menopause and helping so many of us understand whats going on, whats not going on, and how the American medical establishment has a lot of catch-up work to do
Climb to a higher dose and the all-in pushes past $250
J Pediatr Gastroenterol Nutr 1985;4(5):795-798