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136-138 There are no major studies that successfully identify which patients will most likely benefit from surgery, but it is generally considered an appropriate option for patients with a severe, correctable anatomic abnormality

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Important Safety Information: Based on limited human data, it is generally well-tolerated

Published preclinical studies use it as a chemical research tool in cell and animal models investigating ERR signaling, mitochondrial function, cellular respiration, oxidative metabolism, and exercise-response pathways

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