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Basically, when you work out, especially during intense strength training, a component called acetyl CoA is produced in a large amount into the muscles, producing lactate and causing lactate buildup
So far, preclinical and observational data examining the effects of GLP1Ra-based therapies on bone suggest a positive association, whereby GLP1Ra use reduces turnover and promotes bone formation ( 2 (95% CI: 0.01 to 0.04)
Importantly, hypoglycemia risk remains low when GLP-1 receptor agonists are used without insulin or sulfonylureas
I have had no major side effects, but sometimes bad breath
J Thorac Cardiovasc Surg 167(1):329-337.e4, 2024
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