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Nov 2020;31(6):844-851

If you are sensitive to GI effects, the tirzepatide dosing pathway offers a gentler escalation with lower absolute side effect rates at each level

Mounjaro tends to win the Mounjaro vs Ozempic decision for patients who: Have obesity (BMI 30) or are overweight with metabolic risk factors, and weight loss is the primary goal Have an HbA1c that hasnt responded well to metformin or older GLP-1 drugs Dont have a strong personal or family history of cardiovascular disease that specifically needs Ozempics proven protective data Can sustain the higher monthly cost for the 12+ months typically needed for lasting results Who Should Consider Ozempic (or Generic Semaglutide)

Phase 2 (weeks 5-12): The novelty effect fades

Do not self-administer unless specifically instructed and trained by a healthcare provider

Personalized Care for Your Best Results Choosing the right medication is a personal decision that depends on your health profile, preferences, and goals