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Bioactive Materials, 32 , 502-513

Nicotinamide adenine dinucleotide is a naturally occurring chemical and coenzyme that slowly decreases over time

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Decreased cytochrome c oxidase activity but unchanged superoxide dismutase and glutathione peroxidase activities in the spinal cords of patients with amyotrophic lateral sclerosis

18, 19 The nitric oxide (NO) thus produced is a reactive free radical present in cells as a response to increased intracellular concentrations of Ca 2+