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doi: 10.1007/BF02427280 66 NaukMAHeimesaatMMrskovCHolstJJEbertRCreutzfeldt.W

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Glutathione-related enzymes also play a critical role in defense against ROS: (a) glutathione peroxidase (GPX) is a H 2 O 2 scavenger that uses GSH as a reductant, (b) glutathione reductase (GR) reduces GSSG using NADPH as a source of reducing power and maintaining the GSH/GSSG ratio in cells, (c) glutathione-S-transferase (GST) catalyzes the nucleophilic conjugation of GSH with several electrophilic substrates, and (d) glutaredoxins (GRXs), small redox proteins from the thioredoxin (TRX) superfamily, use GSH as electron donor

This could, in turn, support better sperm quality, libido, and overall reproductive function

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