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A vitamin B12 injection introduces the nutrient directly into the bloodstream, bypassing any issues with absorption

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AOD 9604 offers a gentler, side-effect-free approach but with far more modest results and a discontinued development program

Enrolling 17,604 adults aged 45 or older with established cardiovascular disease and a BMI of 27 or higher (without diabetes), SELECT showed that semaglutide 2.4 mg reduced the composite of cardiovascular death, nonfatal myocardial infarction, and nonfatal stroke by 20% over a mean follow-up of nearly 40 months