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L-Carnitine has been extensively studied for its role in energy homeostasis, substrate utilization, and metabolic flexibility
On the other hand, our results indicated that administration of L-carnitine significantly ameliorated the kidney tissue damage and renal function markers such as creatinine, BUN and uric acid
J Ayurveda Integr Med 5(4):251259
Histological analysis revealed smaller adipocytes in gWAT and reduced hepatic steatosis in mice expressing NDI1 in adipocytes (Fig
10.1073/pnas.0511304103 Proc Natl Acad Sci U S A
These studies underscore the paradoxical role of arginine metabolism and availability depending on the circumstances (e.g., immune cells infiltration and the type of arginine metabolizing enzymes expressed in these cells in the TME) and type of tumor, implying that arginine supplementation might be interesting for some, but not other tumors (Table 3)
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